IECB
Seminars
Monday, July 4
Monday, July 4
11 am
11 am
@ IECB auditorium
@ IECB auditorium
Dr. Tomohisa SAWADA
Dr. Tomohisa SAWADA
Laboratory for Chemistry and Life Science, Institute of Innovative Research
Laboratory for Chemistry and Life Science, Institute of Innovative Research
Tokyo Institute of Technology, Japan
Tokyo Institute of Technology, Japan
Metal–peptide rings and nets with entangling topologies
Metal–peptide rings and nets with entangling topologies
Construction of topological molecules has long attracted chemists, yet synthetic strategies for highly complexed topologies remain unexplored to date. In this talk, our recent achievements by using metal–peptide strands will be introduced. Our folding-and-assembly strategy, based on a cooperative processes of peptide self-folding and metal-induced self-assembly, has shed light on the latent entangling nature of peptides and enabled advanced topological nanostructures. Remarkable examples such as torus knots, polyhedral links, and spherical nets will be discussed.
Host: Yann FERRAND
IECB Friday seminars 2022
IECB Friday seminars 2022
March 18, 2022:
March 18, 2022:
Dr. Kevin Macé (Birkbeck college, Institute of Structural and Molecular Biology, UK)
Dr. Kevin Macé (Birkbeck college, Institute of Structural and Molecular Biology, UK)
Title: Type 4 secretion system cryo-EM structures
Title: Type 4 secretion system cryo-EM structures
March 31, 2022:
March 31, 2022:
Dr. Fabienne Burlina (Laboratoire des Biomolécules, Sorbonne Université, Paris)
Dr. Fabienne Burlina (Laboratoire des Biomolécules, Sorbonne Université, Paris)
Title: Extending chemical ligation for the synthesis of proteins: application to NEMO ubiquitylation
Title: Extending chemical ligation for the synthesis of proteins: application to NEMO ubiquitylation
Dr. Yung-Sing Wong (Département de pharmacologie moléculaire, Equipe Chémobiologie et outils moléculaires thérapeutiques, Université Grenoble-Alpes, Grenoble)
Dr. Yung-Sing Wong (Département de pharmacologie moléculaire, Equipe Chémobiologie et outils moléculaires thérapeutiques, Université Grenoble-Alpes, Grenoble)
Title: Benefits of forming spatio-temporal chemical bonds in living environments
Title: Benefits of forming spatio-temporal chemical bonds in living environments
Dr. Leos Valasek (Institute of Microbiology of the Czech Academy of Sciences, Czech Republic)
Dr. Leos Valasek (Institute of Microbiology of the Czech Academy of Sciences, Czech Republic)
Title: Longer is not always the best; lessons from the tRNA anticodon stem
Title: Longer is not always the best; lessons from the tRNA anticodon stem
IECB Friday seminars 2021
IECB Friday seminars 2021
January 12, 2021:
January 12, 2021:
Dr. Hervé Vezin (CNRS - Laboratoire Avancé de Spectroscopie pour les Interactions la Réactivité et l'Environnement (LASIRE), Université de Lille)
Dr. Hervé Vezin (CNRS - Laboratoire Avancé de Spectroscopie pour les Interactions la Réactivité et l'Environnement (LASIRE), Université de Lille)
Title: Advanced EPR spectroscopy in material chemistry for batteries
Title: Advanced EPR spectroscopy in material chemistry for batteries
February 5, 2021:
February 5, 2021:
Dr. Hagen Hofmann (Department of Structural Biology, Weizmann Institute of Science)
Dr. Hagen Hofmann (Department of Structural Biology, Weizmann Institute of Science)
Title: Allostery through DNA drives phenotype switching
Title: Allostery through DNA drives phenotype switching
March 5, 2021:
March 5, 2021:
Prof. Camilo Perez (Biozentrum, University of Basel)
Prof. Camilo Perez (Biozentrum, University of Basel)
Title: Structure and mechanism of a proton dependent lipid transporter involved in lipoteichoic-acids biosynthesis
Title: Structure and mechanism of a proton dependent lipid transporter involved in lipoteichoic-acids biosynthesis
March 18, 2021:
March 18, 2021:
Dr. Michael Eck (Dana-Farber Cancer Institute and Harvard Medical School)
Dr. Michael Eck (Dana-Farber Cancer Institute and Harvard Medical School)
Title: Insights into regulation of the Ras/Raf/MAPk pathway from Cryo-EM Structures of BRAF-MEK-14-3-3 Complexes
Title: Insights into regulation of the Ras/Raf/MAPk pathway from Cryo-EM Structures of BRAF-MEK-14-3-3 Complexes
March 26, 2021:
March 26, 2021:
Dr. Stephan Rauschenbach (University of Oxford)
Dr. Stephan Rauschenbach (University of Oxford)
Title: Electrospray ion beam deposition for single molecule imaging
Title: Electrospray ion beam deposition for single molecule imaging
April 2, 2021:
April 2, 2021:
Prof. Bernard Rentier (Recteur Honoraire, Université de Liège)
Prof. Bernard Rentier (Recteur Honoraire, Université de Liège)
Title: Open Science: Excellence revisited
Title: Open Science: Excellence revisited
April 15, 2021:
April 15, 2021:
Dr. Nora Vazquez-Laslop (University of Illinois at Chicago)
Dr. Nora Vazquez-Laslop (University of Illinois at Chicago)
Title: Macrolide antibiotics as modulators of translation
Title: Macrolide antibiotics as modulators of translation
May 7, 2021:
May 7, 2021:
Dr. Abhishek Chatterjee (Department of Chemistry, Boston College)
Dr. Abhishek Chatterjee (Department of Chemistry, Boston College)
Title: Genetically encoded chemistries to read and write biology
Title: Genetically encoded chemistries to read and write biology
May 28, 2021:
May 28, 2021:
Dr. Julien Gronnier (Center for Plant Molecular Biology, University of Tübingen)
Dr. Julien Gronnier (Center for Plant Molecular Biology, University of Tübingen)
Title: Nanoscale regulation of cell-surface receptor signaling
Title: Nanoscale regulation of cell-surface receptor signaling
June 3, 2021:
June 3, 2021:
Dr. Jonathan Visentin (CHU de Bordeaux, Université de Bordeaux, Immuno ConcEpT, UMR CNRS 5164)
Dr. Jonathan Visentin (CHU de Bordeaux, Université de Bordeaux, Immuno ConcEpT, UMR CNRS 5164)
Title: Surface plasmon resonance to study anti-HLA antibodies: transfer of a basic science method to the bedside of organ transplant recipients and beyond
Title: Surface plasmon resonance to study anti-HLA antibodies: transfer of a basic science method to the bedside of organ transplant recipients and beyond
June 11, 2021:
June 11, 2021:
Prof. Pierre Sonveaux & Prof. Raphaël Frédérick (Université catholique de Louvain)
Prof. Pierre Sonveaux & Prof. Raphaël Frédérick (Université catholique de Louvain)
Title: Discovery of an oxidative pathway of lactate in cancer and its druggability by inhibitors of lactate dehydrogenase 1 (LDH1) oligomerization
Title: Discovery of an oxidative pathway of lactate in cancer and its druggability by inhibitors of lactate dehydrogenase 1 (LDH1) oligomerization
June 11, 2021:
June 11, 2021:
Dr. Alexander Harms (Biozentrum, University of Basel)
Dr. Alexander Harms (Biozentrum, University of Basel)
Title: Drop out or go viral: A story of planned and unplanned expeditions into the phage world
Title: Drop out or go viral: A story of planned and unplanned expeditions into the phage world
June 25, 2021:
June 25, 2021:
Dr. Eric Cornes (Institute Pasteur)
Dr. Eric Cornes (Institute Pasteur)
Title: Non-coding small RNAs as versatile regulators of germline gene expression programs
Title: Non-coding small RNAs as versatile regulators of germline gene expression programs
June 25, 2021:
June 25, 2021:
Dr. Jacob Bobonis (EMBL Heidelberg)
Dr. Jacob Bobonis (EMBL Heidelberg)
Title: Bacterial retrons encode phage-sensing toxin/antitoxin systems
Title: Bacterial retrons encode phage-sensing toxin/antitoxin systems
September 13, 2021:
September 13, 2021:
Dr. Benoit Malleret (National University of Singapore)
Dr. Benoit Malleret (National University of Singapore)
Title: Molecular mechanisms of Plasmodium vivax invasion and cell tropism of zoonotic malaria species
Title: Molecular mechanisms of Plasmodium vivax invasion and cell tropism of zoonotic malaria species
September 22, 2021:
September 22, 2021:
Prof. Valérie de Crécy-Lagard (University of Florida)
Prof. Valérie de Crécy-Lagard (University of Florida)
Title: Linking gene and function by comparative genomics: examples from deazapurine metabolism reveal cross-talks between RNA and DNA modifications
Title: Linking gene and function by comparative genomics: examples from deazapurine metabolism reveal cross-talks between RNA and DNA modifications
October 29, 2021:
October 29, 2021:
Dr. Vishukumar Aimanianda (Institut Pasteur)
Dr. Vishukumar Aimanianda (Institut Pasteur)
Title: Fungal cell-wall polysaccharides, exploiting their translational potential
Title: Fungal cell-wall polysaccharides, exploiting their translational potential
November 26, 2021:
November 26, 2021:
Dr. Niels Fischer (Max Planck Institute for Biophysical Chemistry, Germany)
Dr. Niels Fischer (Max Planck Institute for Biophysical Chemistry, Germany)
Title: Single particle cryo-EM - Towards atomic-resolution of molecular machines in motion
Title: Single particle cryo-EM - Towards atomic-resolution of molecular machines in motion
Dr. Megan Wright (University of Leeds, UK)
Dr. Megan Wright (University of Leeds, UK)
Title: Chemical proteomic tools to study host-microbe interactions
Title: Chemical proteomic tools to study host-microbe interactions