After almost a year break, we restart our traditional IECB Friday Seminars, now via Zoom.

Join us every Friday (sometimes other days) at 11am on zoom broadcast.

Friday, December 3

11 am

via Zoom

Dr. Megan Wright

University of Leeds, UK

Chemical proteomic tools to study host-microbe interactions

Our group develops chemical tools to answer questions about protein function and the mode of action of small molecules in live cells and at the molecular level. We work across organic and peptide synthesis, protein biochemistry, cell biology and quantitative mass spectrometry-based proteomics. We work with scientists from other disciplines to design tools to tackle a range of biological questions – from the mechanisms of antibacterial resistance, to how plants regulate growth, and cancer cell signalling pathways. In this talk I will focus on our development of tools to study host-microbe interactions.

Host: Emmanuelle THINON

Previous seminars

January 12, 2021:

Dr. Hervé Vezin (CNRS - Laboratoire Avancé de Spectroscopie pour les Interactions la Réactivité et l'Environnement (LASIRE), Université de Lille)

Title: Advanced EPR spectroscopy in material chemistry for batteries

February 5, 2021:

Dr. Hagen Hofmann (Department of Structural Biology, Weizmann Institute of Science)

Title: Allostery through DNA drives phenotype switching

March 5, 2021:

Prof. Camilo Perez (Biozentrum, University of Basel)

Title: Structure and mechanism of a proton dependent lipid transporter involved in lipoteichoic-acids biosynthesis

March 18, 2021:

Dr. Michael Eck (Dana-Farber Cancer Institute and Harvard Medical School)

Title: Insights into regulation of the Ras/Raf/MAPk pathway from Cryo-EM Structures of BRAF-MEK-14-3-3 Complexes

March 26, 2021:

Dr. Stephan Rauschenbach (University of Oxford)

Title: Electrospray ion beam deposition for single molecule imaging

April 2, 2021:

Prof. Bernard Rentier (Recteur Honoraire, Université de Liège)

Title: Open Science: Excellence revisited

April 15, 2021:

Dr. Nora Vazquez-Laslop (University of Illinois at Chicago)

Title: Macrolide antibiotics as modulators of translation

May 7, 2021:

Dr. Abhishek Chatterjee (Department of Chemistry, Boston College)

Title: Genetically encoded chemistries to read and write biology

May 28, 2021:

Dr. Julien Gronnier (Center for Plant Molecular Biology, University of Tübingen)

Title: Nanoscale regulation of cell-surface receptor signaling

June 3, 2021:

Dr. Jonathan Visentin (CHU de Bordeaux, Université de Bordeaux, Immuno ConcEpT, UMR CNRS 5164)

Title: Surface plasmon resonance to study anti-HLA antibodies: transfer of a basic science method to the bedside of organ transplant recipients and beyond

June 11, 2021:

Prof. Pierre Sonveaux & Prof. Raphaël Frédérick (Université catholique de Louvain)

Title: Discovery of an oxidative pathway of lactate in cancer and its druggability by inhibitors of lactate dehydrogenase 1 (LDH1) oligomerization

June 11, 2021:

Dr. Alexander Harms (Biozentrum, University of Basel)

Title: Drop out or go viral: A story of planned and unplanned expeditions into the phage world

June 25, 2021:

Dr. Eric Cornes (Institute Pasteur)

Title: Non-coding small RNAs as versatile regulators of germline gene expression programs

June 25, 2021:

Dr. Jacob Bobonis (EMBL Heidelberg)

Title: Bacterial retrons encode phage-sensing toxin/antitoxin systems

September 13, 2021:

Dr. Benoit Malleret (National University of Singapore)

Title: Molecular mechanisms of Plasmodium vivax invasion and cell tropism of zoonotic malaria species

September 22, 2021:

Prof. Valérie de Crécy-Lagard (University of Florida)

Title: Linking gene and function by comparative genomics: examples from deazapurine metabolism reveal cross-talks between RNA and DNA modifications

October 29, 2021:

Dr. Vishukumar Aimanianda (Institut Pasteur)

Title: Fungal cell-wall polysaccharides, exploiting their translational potential

November 26, 2021:

Dr. Niels Fischer (Max Planck Institute for Biophysical Chemistry, Germany)

Title: Single particle cryo-EM - Towards atomic-resolution of molecular machines in motion